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Manufacturers and Developers of IVDs: Improve your Immunoassay Performance and Stability! Professional buffer solutions Made-in-Germany for better immunoassays to help you:

IAXO compounds are Glycolipids and Benzylammonium Lipids designed to act as Lipid A antagonists that potently can inhibit the CD14 and Toll-like Receptor 4 (TLR4) receptors in vitro and in vivo and are innovative drug candidates with therapeutic activity in rodent models of (auto/sterile) inflammatory diseases, neuropathic pain and LPS (endotoxin) induced septic shock.
The novel family of synthetic IAXO compounds [see References] not only can inhibit LPS-stimulated TLR4 activation by competitively occupying CD14 and thereby reducing the delivery of activating endotoxin to MD-2-TLR4 but may also shed light on the features of CD14-dependent and TLR4-independent signalling pathways.


PEVIVA's first-in-class CE-certified cell death biomarker assays M65 ELISA® and M30-Apoptosense® ELISA and the just launched novel broad measuring range version M65 EpiDeath ELISA® have been independently validated by pharmaceutical companies and clinical research centres for diagnostic use in oncology and hepatology.
"Development, production, marketing and sales of biomarker assays to be used for pre-clinical and clinical applications within the fields of hepatology, gastroenterology,organ transplantation, sepsis and cancer" from PEVIVA are quality-certified according to ISO 9001:2008 and ISO 13485:2003.
PEVIVA is the original developer and manufacturer of the well-established M30 CytoDEATHTM monoclonal antibody directed against the caspase-cleaved neo-epitope M30 of Keratin-18 (K18Asp396-NE, ccK18, K18F-M30).
Use the PEVIVA M30 CytoDEATHTM monoclonal antibody provided in a convenient, stabilized stock solution with the widest range of conjugates for FACS, IHC and CTC analysis.